With the help of Xtal Focus…

Proteros obtains CIR accreditation that allows eligible clients to receive 30% of their R&D costs in tax credits

Martinsried February 24, 2012. Proteros biostructures GmbH (“Proteros”) a leading provider of structure-based drug discovery services announced today that it has been awarded CIR accreditation by the French Ministry of Higher Education and Research. The accreditation allows eligible French companies to benefit from significant tax relief (Crédit d’Impôt sur la Recherche) on research carried out by Proteros on their behalf until 2013.

“We are very pleased that our French clients will be able to benefit from the CIR accreditation and the opportunity to receive 30% of their R&D costs in tax credits” said Gordon Woodrow, EVP Strategic Alliances. “Proteros’ clients can access services that range from protein crystallography, kinetic/thermodynamic profiling and custom proteins to fully integrated structure-based lead discovery including proprietary protein-inspired fragment libraries and medicinal chemistry.”

About Proteros

Proteros is a privately held company that provides services and proprietary technologies to support integrated drug discovery. The company accelerates and improves protein structure analysis and structure-based drug discovery with its expertise, industrialized processes and unique technologies for crystallography and fragment-based lead generation. Proteros complements its clients’ internal capabilities with external expertise and access to flexible resources. Proteros currently provides services for more than 60 pharmaceutical and biotechnology clients in North America, Europe and Asia.

For further information please visit the website at: www.proteros.com

Xtal Focus – Protein Crystallization in the spotlight in Germany

UBIFrance Germany Press Release.

With a number of Xtal Focus Systems now installed in Germany, it is not surprising that UBIFrance, the French agency for international business developement in Germany, was curious to find out more about the system and the company.

Xtal Focus is, as UBIFrance puts it, “a simplified process for protein crystallization.” It’s success is due to the modularity of the system and the ability to be customized to suit each laboratory’s needs.

Two additional systems are in the process of being installed in Germany each with the capability of imaging 200 plates per day and each storing in excess of 500 SBS Microplates.  These installations also take the Protein Crystallization experiment a step further, the system is fully automated to assist in the design of the experiments, monitor the location of the plates in the laboratory, control ingredients levels and create worklists for dropsetters/liquid handlers as well as other processes in the Laboratory.

Italy will see the installations of 2 equally impressive systems in January.
Click here to read the complete article by UBIFrance in German.
Request more information on the Xtal Focus Protein Crystal Solution here.

Recent Advances in Macromolecular Crystallization

RAMC 2011 was held Sunday 11 – Wednesday 14 September 2011

Venue: Le Bischenberg Conference Centre near Strasbourg France

 
RAMC is a meeting which aims to identify the latest developments in protein crystallization and provide practical insights to improve methodologies. During the meeting there were lectures, poster sessions, discussion groups, commercial exhibitions and plenty of time for informal interaction.
A successful meeting was had and a special thank you to those that made it happen and to CNRS – Institute of Molecular and Cell Biology (Strasbourg) for allowing us to demonstrate using their Xtal Focus system.

Robustness and reliability…

“The Xtal focus system is a real asset to our crystallization platform. The exceptional quality of the picture allow us to identify very small crystals in our crystallization droplets. The robustness and reliability of the system give us confidence on the quality of observation and leaves us free to focus on our research.”

Jérôme Basquin
Max Planck Institute of Biochemistry – Structural Cell Biology Department
Crystallization and automation platform manager

ICCBM13

The 13th International Conference on the Crystallization of Biological Macromolecules (ICCBM13) was held on the campus of Trinity College Dublin (TCD), Ireland from the 12th to the 16th September 2010. ICCBM13 focused on challenging systems to include macromolecular complexes and membrane proteins with an emphasis on novel practical as well as mechanistic aspects of crystallogenesis.  Many of the leaders in the field shared their knowledge.
The conference catered to the needs of the individual wanting to learn how to grow crystals or to acquire new crystallization skills, the Conference was preceded by a Workshop devoted to hands-on instruction on select aspects of macromolecule production and crystal growth.

PLoS ONE – October 2010

A Graebsch, S Roche, D Kostrewa, J Söding… – 2010 – lmb.uni-muenchen.de
TCEP for the seleno-L-Met-substituted protein. Initial crystallization conditions were screened with a Phoenix nano-dispensing robot and Xtal-focus visualization system. After optimization, crystals were grown at 21uC using
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Biotechnica 2009

Biotechnica 2009 was held in the lovely town of Hannover, Germany. Explora Nova was present to meet and greet and show our latest in Imaging Analysis and Automation. On display was one of the cytomat hotels for use with our Xtal Focus Software for protein crystallization. This cytomat may be used for any other application involving storing and handling SBS Microtitier plates.

Xtal Focus – Protein Crystal Imaging Systems

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The XTal Focus Station is a modular & expandable protein crystal experiment design, imaging & analysis system. Whether you are performing low-throughput or entry level research applications or high-throughput, drug discovery programs the system always guaranteeing an excellent image of crystals at any depth.

XTal Focus provides a simple, yet powerful interface, for viewing images and conditions for evaluation and scoring. Allowing Users to remotely view and score their images over the web or across other platforms such as Mac or PC.

Find out more about Xtal Focus