Define the outlines of regions of interest at low magnification and quantify the cells at high magnification. Apply measurement criterion to assess morphologic, colorimetric, densitometric and stereological analysis. Mercator also eliminates the risk of double counting, and can generate high-resolution maps.
Mercator is compatible with large range of hardware including the latest slide scanners.
The term stereology was coined in 1962 at the first meeting of the International Stereological Society.
Stereological methods concern the estimation of quantitative properties of spatial materials from lower-dimensional information such as that generated by a cross-section of the material.
- the first order stereology estimates quantities as a number, length, surface or volume,
- the second order stereology estimates the spatial organisation of objects.
With Mercator and its stereological module, the microscope becomes a user-friendly tool to obtain these measurements. All these tools are developed and verified in collaboration with Prof C.V.Howard and his team, from The University of Ulster.
The Stereology module gives you a set of convenient, unbiased and efficient tools and methods for quantification of multi-dimensional characteristics of organs, tissues and cells. With the correct sampling strategy, and depending on the orientation of the tissue to be analyzed, this add-on gives you access to a large palette of stereological tools.
See also http://www.unbiased-stereology.com to order the book:
“Unbiased Stereology, 2nd Edition”.